Ingredient
Fermidine®
The Fermented Energy & Longevity Molecule
A next-generation fermented wheat germ extract, standardised to 1% spermidine, clinically studied for cellular renewal, healthy ageing, and cardioprotective effects.
What is Fermidine® Good For?
Fermidine® delivers spermidine, a polyamine supporting autophagy—the body's cellular cleanup process. This helps sustain energy metabolism and cognitive function with age. Fermentation technology enhances spermidine content and stability in wheat germ for consistent nutrient delivery.
Potential benefits of supplementation
- Promotes longevity and healthy aging through autophagy induction and inflammation reduction
- Enhanced mitochondrial energy production in aging stem-cell neurons
- Protection against neurodegeneration and cognitive decline
- Cardioprotective effects by lowering blood pressure
- Promotes skin rejuvenation, hair and nail growth
- Reduces depression
What is Fermedine™ 1% Spermidine?
Spermidine is a naturally occurring polyamine found in wheat germ, soybeans, and mushrooms. It regulates cellular processes including autophagy and protects against DNA damage.
Dietary intake is estimated low for meaningful benefits, so Fermidine™ provides standardized 1% spermidine extract for consistent dosing.
Recommended Daily Dose
100 mg (1% spermidine = ~1 mg spermidine)
Human research indicates 100 mg of wheat germ extract daily, standardised to 1% spermidine (~1 mg spermidine), supports cellular renewal and healthy aging.
Fermidine® in Detail
- Clinical Dose
- 100 mg (1% spermidine = ~1 mg spermidine)
- Source
- Fermented wheat germ extract (Triticum aestivum)
- Technology
- Fermentation + standardisation to 1% spermidine
- Key Benefits
- Stimulates autophagy (the body's cellular renewal system)
- Improves brain, cardiovascular, and metabolic health
- Promotes longevity and resilience with age
- Enhances hair and skin growth
- Reduces depression
- Data
- Supported by peer-reviewed clinical studies on spermidine and longevity pathways.
Supports
Your Questions About Fermidine®
What is Fermidine™?
Fermented, standardised wheat germ extract delivering 1% spermidine, developed by Fermedics for healthy aging and metabolic benefits.
What are the benefits of Fermidine™?
Supports autophagy, promotes cellular renewal, maintains brain, heart, and metabolic health with age.
How does it differ from other spermidine supplements?
Generic products vary in purity and stability; Fermidine™ is fermented, standardised to 1%, manufactured under strict quality controls.
Are there any side effects?
Safe and well-tolerated at recommended dose; consult healthcare professionals if you have health conditions.
How long does it take to work?
Benefits build gradually; research shows measurable effects after 8–12 weeks of consistent use.
The Science That Supports Us
- 1Eisenberg, T. et al. (2009). Induction of autophagy by spermidine promotes longevity. Nature Cell Biology, 11(11), pp. 1305–1314.
- 2Khosroshahi, E.D. and Razavi, S.H. (2023). Spermidine in wheat germ: trends and applications. Trends in Food Science & Technology, 131, pp. 175–189.
- 3Mohajeri, M. et al. (2023). Spermidine and health: a comprehensive review. Food Science & Nutrition, 11(11), pp. 7242–7254.
- 4Schwarz, C. et al. (2018). Spermidine-based nutritional supplementation for the prevention of cognitive decline. Cortex, 109, pp. 181–188.
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