Ingredient
Citrus Bioflavonoids
The Vascular & Antioxidant Protector
A natural complex of flavonoids (hesperidin, naringin, diosmin, rutin) extracted from citrus fruits, clinically studied for cardiovascular health, antioxidant defence, and immune support.
What is Citrus Bioflavonoids Good For?
Citrus bioflavonoids comprise plant compounds from citrus peels and pulp, including hesperidin, naringin, diosmin, and rutin. These bioactives demonstrate scientific evidence for improving circulation, lipid markers, and free radical neutralization.
Potential benefits of supplementation
- Cardiovascular improvements through blood vessel widening in response to increased blood flow
- Reduced oxidative stress and inflammation
- Decreased blood glucose levels and blood pressure in diabetic patients
- Enhanced glucose metabolism and reduced inflammation markers in metformin-treated diabetics
- Improved lipid profiles via reduced LDL cholesterol and triglycerides
- Increased immune defense during viral infection
- Skin UVB protection through inflammation reduction (laboratory studies)
What is Citrus Bioflavonoids?
Bioflavonoids are polyphenolic compounds widely distributed in fruits and vegetables. Citrus-derived flavonoids are well-studied for cardiovascular health, capillary resistance effects, and enhanced vitamin C absorption.
Recommended Daily Dose
500 mg
Human studies commonly employ 500 mg daily, alone or combined with vitamin C, to support cardiovascular health, antioxidant capacity, and immune defense.
Citrus Bioflavonoids in Detail
- Clinical Dose
- 500 mg
- Source
- Citrus fruit peel and pulp (oranges, lemons, grapefruits)
- Technology
- Standardised extraction for key flavonoids
- Key Benefits
- Strengthens capillaries and improves microcirculation
- Works synergistically with vitamin C to support immune health
- Provides antioxidant and anti-inflammatory protection
- Supports collagen stability and skin health
- Contributes to cardiovascular and metabolic balance
- Data
- Supported by clinical studies on blood circulation improvement, oxidative stress reduction, and immunity.
Supports
Your Questions About Citrus Bioflavonoids
What are Citrus Bioflavonoids?
Natural plant compounds from citrus fruits supporting vascular integrity, antioxidant defense, and immune health.
What are the benefits?
Blood vessel protection, oxidative stress reduction, enhanced vitamin C absorption, and cardiovascular and immune support.
How do they differ from synthetic antioxidants?
Unlike isolated antioxidants, citrus bioflavonoids work synergistically with vitamin C and provide broad-spectrum plant-based protective compounds.
Are there side effects?
Generally well-tolerated; high doses may cause mild digestive discomfort.
Can they combine with vitamin C?
Yes, citrus bioflavonoids may enhance vitamin C absorption and provide synergistic immune support.
The Science That Supports Us
- 1Bellavite, P. & Donzelli, A. (2020). Hesperidin and SARS-COV-2: citrus fruit health functions. Journal of Integrative Medicine.
- 2Cesar, T.B. et al. (2025). Citrus flavonoid supplementation effects on glycemic control in prediabetic metformin patients. Nutrients.
- 3Gandhi, G.R. et al. (2020). Citrus flavonoids targeting diabetes complications: a systematic review. Journal of Ethnopharmacology.
- 4Gupta, A. et al. (2023). Citrus bioflavonoid supplementation mechanisms for blood glucose and metabolic complications. Critical Reviews in Food Science and Nutrition.
- 5Jalili, C. et al. (2024). Citrus flavonoids and endothelial function: a meta-analysis. Phytotherapy Research.
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