Alpha Lipoic Acid

The Universal Antioxidant

A clinically studied antioxidant that improves cellular energy production, nerve functions, and metabolic homeostasis.

What is Alpha Lipoic Acid Good For?

Alpha Lipoic Acid (ALA) is a naturally occurring compound made in small amounts by multiple organs in the body. It is also naturally present in foods such as spinach, broccoli, and organ meats. Known as the “universal antioxidant”, ALA is both water- and fat-soluble, meaning it can be more easily absorbed and utilised by cells and tissues in the body.

 

ALA supplementation may lead to:

  • Improved blood sugar metabolism
  • Increased energy production in the mitochondria
  • Better nerve function in people living with diabetes
  • Enhancing liver detoxification pathways
  • Improved antioxidant defence that otherwise declines with aging
  • Enhanced mitochondrial function by recycling cellular antioxidants and vitamins C & E

     

What is Alpha Lipoic Acid?

Alpha Lipoic Acid is a disulfide compound that plays a central role in mitochondrial energy metabolism. As a cofactor it helps enzymes to convert nutrients into energy and neutralises free radicals throughout the body.

 

Supplemental ALA provides higher levels than dietary sources alone and has been widely researched for its role in glucose metabolism and diabetic neuropathy.

What is the Recommended Daily Dose of Alpha Lipoic Acid?

Human clinical studies suggest that 600 mg daily Alpha Lipoic Acid improves nerve functions, antioxidant defence, and metabolic processes. Lower doses (100–300 mg) are also commonly used for maintaining ALA levels.

Things to Know

Source

Endogenously produced in small amounts; also found in plants and animal foods

Technology

Available as synthetic racemic ALA or as R-ALA (the naturally occurring isomer, with higher activity)

Region

Widely used in clinical nutrition and dietary supplementation

Data

Supported by peer-reviewed human clinical trials, particularly in nerve health and metabolic function

Alpha Lipoic Acid in Detail

Clinical Dose
Clinical Dose

600 mg

Source
Source

Alpha Lipoic Acid (endogenous antioxidant compound)

Technology
Technology

Dual solubility (fat- and water-soluble) allows broad cellular action; available in racemic and R-isomer forms

Key Benefits
Key Benefits
  • Universal antioxidant working in all tissues
  • Supports blood sugar homeostasis and insulin sensitivity
  • Protects nerves and supports neuropathic health
  • Recycles vitamins C & E, extending antioxidant protection
  • Enhances mitochondrial energy production
Data
Data

Over 20 years of human clinical research supporting use in metabolic and nerve health

Your Questions About Alpha Lipoic Acid

Reach us arrow_forward
ALA is a naturally occurring compound that helps enzymes convert nutrients into energy while acting as a universal antioxidant.
It supports nerve health, balances blood sugar, enhances antioxidant defence, and contributes to energy metabolism.
Unlike most antioxidants, ALA is both water- and fat-soluble, allowing it to work in every part of the cell and regenerate other antioxidants.
ALA is generally well tolerated. At higher doses, some individuals may experience mild digestive discomfort. People with diabetes should consult their doctor before use due to its blood sugar–lowering effects.
Yes, ALA complements antioxidants like vitamins C & E and works synergistically with nutrients supporting mitochondrial processes.

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References

The Science That Supports Us

Cognitive and Neurological Support

Liu, J. (2007) ‘The effects and mechanisms of mitochondrial nutrient α-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: An overview’, Neurochemical Research, 33(1), pp. 194–203. doi:10.1007/s11064-007-9403-0.

Mental Health

Vallianou, N., Evangelopoulos, A. and Koutalas, P. (2010) ‘Alpha-lipoic acid and diabetic neuropathy’, The Review of Diabetic Studies, 6(4), pp. 230–236. doi:10.1900/rds.2009.6.230.

Nerve Repair

Shay, K.P. et al. (2009) ‘Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential’, Biochimica et Biophysica Acta (BBA) - General Subjects, 1790(10), pp. 1149–1160. doi:10.1016/j.bbagen.2009.07.026.