Ingredient

Levagen+®

The Next-Generation Palmitoylethanolamide (PEA)

A patented, highly bioavailable form of PEA using LipiSperse® delivery technology, clinically studied to reduce inflammation, joint pain, muscle recovery time, and improve sleep.

What is Levagen+® Good For?

Levagen+® is a naturally occurring fatty acid amide that activates the endocannabinoid system (ECS) and peroxisome proliferator-activated receptor α (PPAR-α). It is clinically shown to reduce pain, inflammation and improve sleep quality. Using LipiSperse® delivery technology, it addresses low solubility and absorption issues of standard PEA, delivering clinically proven higher bioavailability.

Potential benefits of supplementation

  • Decrease joint pain
  • Reduce migraine pain and duration
  • Reduce inflammation by activating PPAR-α and transient receptor vanilloid type 1 (TRPV1)
  • Improve allergic rhinitis symptoms by reducing histamine and inflammation markers
  • Muscle recovery through lowered myoglobin and blood lactate levels
  • Reduce upper respiratory tract infections
  • Fall asleep faster and improve cognition upon waking

What is Levagen+®?

PEA is an endogenously produced fatty acid amide discovered in the 1950s. It naturally regulates inflammation and pain pathways, functioning as a protective molecule during stress and injury.

Levagen+® uses LipiSperse® delivery technology to enhance bioavailability, addressing the low solubility issues of standard PEA. It can be used safely alongside CBD without psychoactive effects.

Recommended Daily Dose

300

300 mg

300 mg daily for joint pain, inflammation reduction, and sleep improvement. Doses up to 600 mg/day have been studied for enhanced benefits.

Levagen+® in Detail

Clinical Dose
300 mg
Source
Palmitoylethanolamide (PEA) — naturally occurring fatty acid amide
Technology
Patented LipiSperse® delivery system for enhanced absorption
Key Benefits
  • Clinically proven to improve absorption vs. standard PEA
  • Lowers joint pain and reduces migraine pain/duration
  • Reduces inflammation and aids exercise recovery
  • Helps to fall asleep and improves cognition upon waking
  • Reduces upper respiratory tract infections
Data
Supported by seven peer-reviewed clinical studies covering allergic rhinitis, migraine, joint pain, exercise recovery, respiratory infections, and sleep.

Supports

Sleep Quality & RestorationImmunity & Defense

Your Questions About Levagen+®

What is Levagen+®?

A patented, bioavailable form of PEA using LipiSperse® delivery technology for enhanced absorption and clinical efficacy.

What are the benefits?

Reduces joint pain, inflammation, migraine duration, and improves sleep quality and immune defense.

How is it different from standard PEA?

Levagen+® uses LipiSperse® technology to dramatically improve absorption compared to standard PEA formulations.

Are there any side effects?

PEA is safe and well tolerated. No significant adverse effects reported in clinical trials.

Can it be combined with CBD?

Yes, Levagen+® can be used safely alongside CBD. It supports the endocannabinoid system without psychoactive effects.

The Science That Supports Us

  1. 1Levagen clinical research team (2020). Levagen+® effects on allergic rhinitis symptoms. Nutrients.
  2. 2Levagen clinical research team (2021). Palmitoylethanolamide effects on migraine pain reduction. Pharmaceuticals.
  3. 3Levagen clinical research team (2020). PEA for exercise recovery and muscle soreness. British Journal of Pharmacology.
  4. 4Levagen clinical research team (2021). Palmitoylethanolamide effects on sleep quality. Sleep Science and Practice.

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